Principal Project Manager

Ascent Services Group

Boulder, CO, USA

Full time

Jan 1

The Principal Project Manager is responsible for engineering projects portfolio of GMP biopharmaceutical manufacturing and development sites. Projects include multiple small (<$1M) and large capital projects. Projects may include manufacturing facility expansions and improvements, equipment replacements, clean utilities, laboratories, warehouse, and administrative spaces.


  • The Principal Project Manager develops and follows sound project delivery methodologies through the project lifecycle: charter, concept design, basic design, detail design, construction, and qualification; the Principal Project Manager provides leadership of project engineers and multi-disciplined engineering teams, oversees project cost and schedule controls, and administers contracts
  • The Principal Project Manager interacts extensively with internal stakeholders, external service providers and vendors, clients, and senior management to ensure alignment on requirements, scope, schedule, and management of issues/risks; developing strategy, capital plans, and portfolio management is also within the job scope
  • The Principal Project Manager works to ensure alignment and coordination across sites and other functions such as Engineering, Validation, Maintenance, Manufacturing, Process Development, Analytical Services, and Quality Assurance; leads efforts of the organization across functional boundaries; represents the functional area to clients, auditors, and inspectors
  • Oversees project engineering portfolio for multiple systems, processes, or areas; develops subject matter experts in several areas; applies advanced approaches to develop and implement strategies, technologies, or other major improvements; directs, reviews, and approves engineering documents


  • BS in Chemical Engineering or Mechanical Engineering; advanced degree a plus
  • 8+ years of experience in the pharmaceutical industry in engineering or project management
  • Proven knowledge of cGMP manufacturing processes and related codes and regulations
  • Management and leadership of small teams and external service providers
  • A track record of managing project managers and engineers for delivery of quality projects on-time and budget
  • Solid experience developing and using portfolio and project management and control tools (e.g. chartering, project planning, schedule, estimating, cost, risk management, etc. )
  • Acumen and experience in supporting functional teams to develop business case
  • Strong understanding of project delivery methods and processes during each project phase (initiation, design, procurement, construction, commissioning, qualification, and start-up), lean construction, contracts, stakeholder management, communication, team building, etc
  • Excellent communication skills across a wide range of audiences
  • Pharmaceutical facility design experience in an engineering consulting firm desired
  • Design and construction of cGMP systems
  • Project management professional certification

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